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Although those are the best for muscle growth, you will also see good development of muscles using S4 Andarine and LGD-4033 Ligandrolone Aspartate (LAA). The LAA is derived from the same amino acid as ARA in the muscle, which is why it is used in both.
If you are using the LAA in its natural form in your supplements, you are likely to notice an immediate boost in lean mass and muscularity. Not only will your workout be much easier and more intense, but you will see a more intense increase in glycogen loading during your workouts, thus making it easier to sustain your weight loss while still performing well.
This study was a recent meta-analysis of over 3,000 studies that compared SAA vs LAA supplementation, providing additional evidence showing that SFA can result in more muscle growth.
Another meta-analysis revealed a 6.1% increase in muscle muscle fiber fractional anabolism after a 24-wk supplementation period, with no statistically significant differences between SAA and LAA. This is a much larger increase in muscle protein synthesis than what is seen with the more common glutamine used in other forms of supplementation. Aspartate and cysteine are also known to increase protein synthesis.
While not necessarily a good choice for everyone, both SAA and LGD-4033 have been shown to effectively promote muscle growth in humans. So if your goal is to gain lean muscle mass, this is definitely a supplement you need to take in your diet.
For more information on LAA, you may want to check out this study on this topic.
How Can LAA Damage Muscle?
There have been studies that demonstrate that high doses of LAA could have a negative effect on muscle growth, especially when used in combination with the BCAAs.
In one recent study, high doses of LAA were found to result in damage to the mitochondria in the muscle of mice. This damage was found to be caused by the mitochondria breaking down LAA, which is not the LAA that would be used by muscle cells for energy.
The damage from the LAA was so severe that it caused a decrease in ATP production in the muscle of the mice, and this decrease in ATP was followed by an increase in fat utilization instead of protein synthesis.
This was even more shocking, but these mice had high levels of LAA circulating in their blood, since there is currently no good control for high levels of LAA in a healthy body.
Interestingly, there are other proteins in your body that also break down LAA-
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